One of the powerful functionality of Zabbix Monitoring System is the use of Rest API for interacting with the frontend
You can create/delete/update an host and modifying a lot of parameters using , for example, a python script for automating some task and procedure.
First of all you have to verify that a API is full operational on your frontend. For simplicity we will use a curl for sending a POST request:
curl -H "Content-Type: application/json-rpc" -X POST http://zabbix/zabbix/api_jsonrpc.php -d '{"jsonrpc":"2.0","method":"apiinfo.version","id":1,"auth":null,"params":{}}'
the result should be this :
{"jsonrpc":"2.0","result":"4.0.3","id":1}
Go ahead!
Now we have to retrieve a token :
curl -H "Content-Type: application/json-rpc" -X POST https://zabbix/zabbix//api_jsonrpc.php -d '{"jsonrpc":"2.0","method":"user.login","id":1,"auth":null,"params":{"user":"Admin","password":"zabbix"}}'
and the result :
{"jsonrpc":"2.0","result":"9be759b144adeea966225a7e901","id":1}
Now with the token is possible to send what you want
In this example we retrieve a list of host :
curl -H "Content-Type: application/json-rpc" -X POST http://zabbixn/zabbix/api_jsonrpc.php -d '{"jsonrpc":"2.0","method":"host.get","id":1,"auth":"9be759b144adeea966225a7e901","params":{"output":["host"]}}'
the result is ever in a json format.
Here the official documentation of Rest API, you have to choose the correct version of your installation